Panther Fusion® GBS Assay

Assay box on table in lab setting

    Overview

    Documents

    Training

    Accurate Group B Strep Screening using PCR NAAT: A Test You Can Trust

    With performance you can trust, the Panther Fusion® GBS assay transforms your laboratory workflow and expands the molecular menu on the Panther Fusion® system. The assay detects the gram-positive bacterium Streptococcus agalactiae (GBS) from antepartum women, which demonstrated 100% sensitivity.1 

    Graphic showing 100% Sensitivity
    Pregnant woman in office setting.

    Identify more true positive GBS mothers with a highly sensitive NAAT

    ACOG and ASM guidelines suggest that all pregnant women be screened for GBS. Research indicates that screening with NAATs is highly sensitive and offers improved workflow and faster results compared to culture. Studies have shown that the Panther Fusion® GBS assay detects 31% more positives than culture, with less than 1 minute of hands-on time.2,3,4

    Video Resources

    The Panther Fusion GBS assay design1

    Illustration of a DNA

    Detects Group B Streptococcus DNA from antepartum women, following an 18–24-hour incubation in selective enrichment broth culture of Lim Broth or Carrot Broth

    Illustration of a target

    Features dual-target detection of the Cfb and SIP genes, showing 100% clinical sensitivity and 96.5% specificity in a clinical trial.

    Assay Specifications

    Screening window:

    Antepartum women

    Specimen type:

    Single vaginal-rectal swab3

    Media Type:

    Liquid Stuart's or Amies

    Enrichment broth:

    Lim Broth or Carrot Broth

    Turnaround time (TAT):

    Quick TAT, <2.4 hours5

    Saving Lives Through Accurate Detection: An Overview of GBS Screening Guidelines During Pregnancy

    Lab Technician Diagnostics Testing
    book icon

    Panther Fusion® GBS Assay: Testing the Benefits of NAATs versus Culture for Group B Strep Screening

    Pregnant Woman Doctor Screening

    The Latest News on Panther Fusion GBS Assay

    Lab techs looking with confidence in a lab

    See the Complete Picture with PCR NAAT for Group B Strep

    Mother and Child image

    Supporting more accurate GBS screening: Getting better results with a nucleic acid amplified test (NAAT)

    Group of attendees standing together inside for a photo

    The Subject of Women's Health Tops the Agenda at Goals House, Davos

    How much time and money could you save?

    The Panther Fusion GBS assay run on the Panther Fusion system offers: 

    • Full automation 
    • High throughput  
    • Ready-to-use reagents with 30-60 day on board stability, eliminating reagent prep and waste1
    • A non-batch workflow 

    Consolidate your group B strep testing on the Panther Fusion system with other Aptima® and Panther Fusion® assays for women's health, virology, respiratory and sexually transmitted infections.

    Lab tech walking to Panther system
      1. Panther Fusion GBS assay. US package insert AW-23714-001. Hologic, Inc.; 2022. 2. Shin JH and Pride DT. Comparison of Three Nucleic Acid Amplification Tests (NAATs) and Culture for Detection of Group B Streptococcus (GBS) from Enrichment Broth. J Clin Microbiology JCM.01958-18; DOI: 10.1128/JCM.01958-18 3. American Society for Microbiology. Guidelines for the Detection and Identification of Group B Streptococcus. ASM.org website. Last reviewed July 23, 2021. Accessed April 27,2023. https://asm.org/ASM/media/Protocol-Images/ASM-GBS-guideline.pd 4. Berry GJ, et al. Comparison of the Panther Fusion and BD MAX GBS Assays for Detection of Group B Streptococcus in Prenatal Screening Specimens. J Clin Microbiol. 2019; JCM.01034-19.     5. Data on file